I find the factory recommended idle mixture screw setting specs to be very close to ideal. They are listed here for the Honda GL1000.
I do usually richen them up an extra 1/8 to 1/4 turn (out) to compensate for the leaner modern “gasoline” which is diluted with ethanol in most US markets.
But sometimes, you just need an excuse to do some high performance tuning on your bike! 🙂